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Beneficial effects of pioglitazone against cardiovascular injury are enhanced by combination with aliskiren in a rat model of diabetic nephropathy.
Elrashidy RA, Asker ME, Mohamed HE.
J Pharm Pharmacol. 2012 Jun;64(6):862-71. doi: 10.1111/j.2042-7158.2012.01508.x. Epub 2012 Mar 30
22571265
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Aliskiren Reduces Morning Blood Pressure in Hypertensive Patients with Diabetic Nephropathy.
Takenaka T, Nobe K, Okayama M, Kojima E, Nodaira Y, Sueyoshi K, Hoshi H, Watanabe Y, Takane H, Suzuki H.
Clin Exp Hypertens. 2012 May 4. [Epub ahead of print
22559034
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Aliskiren Prevents the Toxic Effects of Peritoneal Dialysis Fluids during Chronic Dialysis in Rats.
Pérez-Martínez J, Pérez-Martínez FC, Carrión B, Masiá J, Ortega A, Simarro E, Nam-Cha SH, Ceña V.
PLoS One. 2012;7(4):e36268. Epub 2012 Apr 27
22558414
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Failure to intensify hypertension therapy after rejected aliskiren claims.
Zeng F, Park J, Plauschinat CA, Patel BV.
Clin Ther. 2012 May;34(5):1122-31. Epub 2012 Apr 27
22541588
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Emerging drug combinations to optimize renovascular protection and blood pressure goals.
Escobar C, Echarri R, Barrios V.
Int J Nephrol Renovasc Dis. 2012;5:69-80. Epub 2012 Apr 3
22536084
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Long-term effects of aliskiren on blood pressure and the renin-angiotensin-aldosterone system in hypertensive hemodialysis patients.
Morishita Y, Watanabe M, Hanawa S, Iimura O, Tsunematsu S, Ishibashi K, Kusano E.
Int J Nephrol Renovasc Dis. 2012;5:45-51. Epub 2012 Mar 21
22536081
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Comparative Efficacy of Aliskiren/Valsartan vs Valsartan in Nocturnal Dipper and Nondipper Hypertensive Patients: A Pooled Analysis.
Giles TD, Alessi T, Purkayastha D, Zappe D.
J Clin Hypertens (Greenwich). 2012 May;14(5):299-306. doi: 10.1111/j.1751-7176.2012.00608.x. Epub 2012 Mar 16
22533656
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How well do aliskiren's purported mechanisms track its effects on cardiovascular and renal disorders?
Jagadeesh G, Balakumar P, Stockbridge N.
Cell Signal. 2012 Apr 13;24(8):1583-1591. [Epub ahead of print
22522051
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Contrasting effects of aliskiren versus losartan on hypertensive vascular remodeling.
Martins-Oliveira A, Castro MM, Oliveira DM, Rizzi E, Ceron CS, Guimaraes D, Reis RI, Costa-Neto CM, Casarini DE, Ribeiro AA, Gerlach RF, Tanus-Santos JE.
Int J Cardiol. 2012 Apr 5. [Epub ahead of print
22483258
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Use of direct renin inhibitor in an HIV positive subject.
Ucciferri C, Brescini L, Staffolania S, Falasca K, Cirioni O, Giacometti A, Vecchiet J.
Infez Med. 2012 Mar;20(1):49-51
22475660
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Rapid HILIC method with fluorescence detection using derivatization reaction utilizing o-phthaldialdehyde for determination of degradation product of aliskiren.
Douša M, Břicháč J, Svoboda J, Klvaňa R.
J Pharm Biomed Anal. 2012 Mar 17. [Epub ahead of print
22475518
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Combination of direct renin inhibition with angiotensin type 1 receptor blockade improves aldosterone but does not improve kidney injury in the transgenic Ren2 rat.
Whaley-Connell A, Habibi J, Nistala R, Hayden MR, Pulakat L, Sinak C, Locher B, Ferrario CM, Sowers JR.
Regul Pept. 2012 Jun 10;176(1-3):36-44. Epub 2012 Mar 29
22465166
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Effect of Direct Renin Inhibitor, Aliskiren, on Peripheral Blood Monocyte Subsets and Myocardial Salvage in Patients With Primary Acute Myocardial Infarction.
Ozaki Y, Imanishi T, Tanimoto T, Kashiwagi M, Tsujioka H, Sougawa H, Orii M, Shiono Y, Shimamura K, Ishibashi K, Komukai K, Ino Y, Kitabata H, Akasaka T.
Circ J. 2012 Mar 28. [Epub ahead of print
22453004
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Effect of aliskiren treatment on endothelium-dependent vasodilation and aortic stiffness in essential hypertensive patients.
Virdis A, Ghiadoni L, Qasem AA, Lorenzini G, Duranti E, Cartoni G, Bruno RM, Bernini G, Taddei S.
Eur Heart J. 2012 Mar 26. [Epub ahead of print
22450428
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Sustained decrease in blood pressure following missed doses of aliskiren or telmisartan: the ASSERTIVE double-blind, randomized study.
Düsing R, Brunel P, Baek I, Baschiera F.
J Hypertens. 2012 May;30(5):1029-40
22441345
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Aliskiren, ALTITUDE, and the implications for ATMOSPHERE.
McMurray JJ, Abraham WT, Dickstein K, Køber L, Massie BM, Krum H.
Eur J Heart Fail. 2012 Apr;14(4):341-3. No abstract available.
22431404
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Key advances in antihypertensive treatment.
Paulis L, Steckelings UM, Unger T.
Nat Rev Cardiol. 2012 Mar 20;9(5):276-85. doi: 10.1038/nrcardio.2012.33
22430830
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Aliskiren as a novel therapeutic agent for hypertension and cardio-renal diseases.
Rashikh A, Ahmad SJ, Pillai KK, Najmi AK.
J Pharm Pharmacol. 2012 Apr;64(4):470-81. doi: 10.1111/j.2042-7158.2011.01414.x. Epub 2011 Dec 7
22420653
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Influence of diabetes on efficacy of aliskiren, losartan or both on left ventricular mass regression.
Vardeny O, Pouleur AC, Takeuchi M, Appelbaum E, Verma A, Prescott M, Smith B, Dahlof B, Solomon SD.
J Renin Angiotensin Aldosterone Syst. 2012 Mar 13. [Epub ahead of print
22415888
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Solid-state nuclear magnetic resonance study of the physical stability of electrospun drug and polymer solid solutions.
Brettmann BK, Myerson AS, Trout BL.
J Pharm Sci. 2012 Jun;101(6):2185-93. doi: 10.1002/jps.23107. Epub 2012 Mar 12
22411707
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