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Perifosine sensitizes UVB-induced apoptosis in skin cells: New implication of skin cancer prevention?
Ji C, Yang YL, Yang Z, Tu Y, Cheng L, Chen B, Xia JP, Sun WL, Su ZL, He L, Bi ZG.
Cell Signal. 2012 May 11. [Epub ahead of print
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DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells.
Haynes TA, Filippov V, Filippova M, Yang J, Zhang K, Duerksen-Hughes PJ.
Biochim Biophys Acta. 2012 Feb 11;1821(7):943-953. [Epub ahead of print
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Alcohol, insulin resistance and the liver-brain axis.
de la Monte S, Derdak Z, Wands JR.
J Gastroenterol Hepatol. 2012 Mar;27 Suppl 2:33-41. doi: 10.1111/j.1440-1746.2011.07023.x
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Resuscitating wild-type p53 expression by disrupting ceramide glycosylation: a novel approach to target mutant p53 tumors.
Liu YY.
Cancer Res. 2011 Oct 15;71(20):6295-9. Epub 2011 Oct 4. Review
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Ablation of sphingosine kinase-2 inhibits tumor cell proliferation and migration.
Gao P, Smith CD.
Mol Cancer Res. 2011 Nov;9(11):1509-19. Epub 2011 Sep 6
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Defining a role for sphingosine kinase 1 in p53-dependent tumors.
Heffernan-Stroud LA, Helke KL, Jenkins RW, De Costa AM, Hannun YA, Obeid LM.
Oncogene. 2012 Mar 1;31(9):1166-75. doi: 10.1038/onc.2011.302. Epub 2011 Jul 18
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Glutathione selectively inhibits Doxorubicin induced phosphorylation of p53Ser¹⁵, caspase dependent ceramide production and apoptosis in human leukemic cells.
Thayyullathil F, Chathoth S, Kizhakkayil J, Galadari A, Hago A, Patel M, Galadari S.
Biochem Biophys Res Commun. 2011 Jul 22;411(1):1-6. Epub 2011 Jun 6
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Serine palmitoyltransferase inhibitor myriocin induces growth inhibition of B16F10 melanoma cells through G(2) /M phase arrest.
Lee YS, Choi KM, Choi MH, Ji SY, Lee S, Sin DM, Oh KW, Lee YM, Hong JT, Yun YP, Yoo HS.
Cell Prolif. 2011 Aug;44(4):320-9. doi: 10.1111/j.1365-2184.2011.00761.x. Epub 2011 Jun 6
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Differential apoptotic effects of novel quinuclidinone analogs 8a and 8b in normal and lung cancer cell lines.
Malki A, Bergmeier S.
Anticancer Res. 2011 Apr;31(4):1345-57
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Novel quinuclidinone derivative 8a induced apoptosis in human MCF-7 breast cancer cell lines.
Malki A, Bergmeier SC.
Anticancer Res. 2011 Mar;31(3):871-80
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Resveratrol, a phytochemical inducer of multiple cell death pathways: apoptosis, autophagy and mitotic catastrophe.
Delmas D, Solary E, Latruffe N.
Curr Med Chem. 2011;18(8):1100-21. Review
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Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells.
Liu YY, Patwardhan GA, Bhinge K, Gupta V, Gu X, Jazwinski SM.
Cancer Res. 2011 Mar 15;71(6):2276-85. Epub 2011 Jan 28
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[HIV-1 neuropathogenesis: therapeutic strategies against neuronal loss induced by gp120/Tat glycoprotein in the central nervous system].
Merino JJ, Montes ML, Blanco A, Bustos MJ, Oreja-Guevara C, Bayon C, Cuadrado A, Lubrini G, Cambron I, Munoz A, Cebolla S, Gutierrez-Fernandez M, Bernardino JI, Arribas JR, Fiala M.
Rev Neurol. 2011 Jan 16;52(2):101-11. Review. Spanish.
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Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands.
van Waarde A, Rybczynska AA, Ramakrishnan N, Ishiwata K, Elsinga PH, Dierckx RA.
Curr Pharm Des. 2010;16(31):3519-37. Review
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p53 and regulation of bioactive sphingolipids.
Heffernan-Stroud LA, Obeid LM.
Adv Enzyme Regul. 2011;51(1):219-28. Epub 2010 Oct 28. Review
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Short-term magnesium deficiency upregulates sphingomyelin synthase and p53 in cardiovascular tissues and cells: relevance to the de novo synthesis of ceramide.
Altura BM, Shah NC, Li Z, Jiang XC, Zhang A, Li W, Zheng T, Perez-Albela JL, Altura BT.
Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H2046-55. Epub 2010 Oct 8
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Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy.
Lépine S, Allegood JC, Park M, Dent P, Milstien S, Spiegel S.
Cell Death Differ. 2011 Feb;18(2):350-61. Epub 2010 Aug 27
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Additive effects of C(2)-ceramide on paclitaxel-induced premature senescence of human lung cancer cells.
Chen JY, Hwang CC, Chen WY, Lee JC, Fu TF, Fang K, Chu YC, Huang YL, Lin JC, Tsai WH, Chang HW, Chen BH, Chiu CC.
Life Sci. 2010 Sep 11;87(11-12):350-7. Epub 2010 Jul 17
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Inhibition of p53 sensitizes MCF-7 cells to ceramide treatment.
Struckhoff AP, Patel B, Beckman BS.
Int J Oncol. 2010 Jul;37(1):21-30
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Nitrosative stress as a mediator of apoptosis: implications for cancer therapy.
Hirst DG, Robson T.
Curr Pharm Des. 2010 Jan;16(1):45-55. Review
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