About The Medical Condition Acetazolamide
Find the definition of the medical term Acetazolamide. Acetazolamide defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Acetazolamide
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What's The Definition Of The Medical Condition Acetazolamide?
One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
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