About The Medical Condition Activated Factor VIII
Find the definition of the medical term Activated Factor VIII. Activated Factor VIII defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Activated Factor VIII
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What's The Definition Of The Medical Condition Activated Factor VIII?
Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similiar in structure and generation to factor Va.
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