About The Medical Condition Aflatoxin M1
Find the definition of the medical term Aflatoxin M1. Aflatoxin M1 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Aflatoxin M1
Aflatoxin M1 Medical Condition |
---|
What's The Definition Of The Medical Condition Aflatoxin M1?
A 4-hydroxylated metabolite of AFLATOXIN B1, one of the MYCOTOXINS from ASPERGILLUS tainted food. It is associated with LIVER damage and cancer resulting from its P450 activation to the epoxide which alkylates DNA. Toxicity depends on the balance of liver enzymes that activate it (CYTOCHROME P-450) and others that detoxify it (GLUTATHIONE S TRANSFERASE) (Pharmac Ther 50.443 1991). Primates & rat are sensitive while mouse and hamster are tolerant (Canc Res 29.236 1969).
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Line Management, Product ‐ Management control systems for structuring health care delivery…
- Hepatic Duct ‐ Predominantly extrahepatic bile duct which is formed by the junction…
- Nonacceptors ‐ The seeking and acceptance by patients of…
- Pregnant Mares Serum ‐ Polypeptide hormones secreted in pregnant mares at the junction…
- Mutagenesis, Viral Insertional ‐ Mutagenesis where the mutation is caused by the introduction…
- Information System, Radiologic ‐ Information systems, usually computer-assisted, designed to store,…
- Epidermolysis Bullosa ‐ Group of genetically determined disorders characterized by the…
- Ketosuccinates ‐ Salts and esters of…
- Kyasanur Forest disease virus ‐ A subgroup of the genus FLAVIVIRUS that causes encephalitis and…
- DNA Nucleotidylexotransferase ‐ A non-template-directed DNA polymerase normally found in vertebrate…