About The Medical Condition Alkylating Antineoplastic Agents
Find the definition of the medical term Alkylating Antineoplastic Agents. Alkylating Antineoplastic Agents defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Alkylating Antineoplastic Agents
| Alkylating Antineoplastic Agents Medical Condition |
|---|
What's The Definition Of The Medical Condition Alkylating Antineoplastic Agents?
A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA, Drug Evaluations Annual, 1994, p2026)
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Antigens, HLA-BR ‐ A group of D-related human leukocyte antigens that are polymorphic…
- Gene Expression Microarray Analysis ‐ Hybridization of a nucleic acid sample to a very large set of…
- Organization, Nongovernmental ‐ Administration and functional structures for the purpose of collectively…
- Pieces, Protective Mouth ‐ Devices or pieces of equipment placed in or around the mouth…
- Sphincterotomies, Transduodenal ‐ Surgery of the smooth muscle sphincter of the hepatopancreatic…
- Diabetic Neuropathy ‐ Peripheral, autonomic, and cranial nerve disorders that are associated…
- Cystitis, Chronic Interstitial ‐ A condition of the bladder occurring predominantly in women,…
- Occupational Noises ‐ Noise present in occupational, industrial, and factory…
- Arnold-Chiari Malformation, Type I ‐ A group of congenital malformations involving the brainstem,…
- Electromagnetic Radiation, Non-Ionizing ‐ Electromagnetic radiation which does not produce ions in matter…