About The Medical Condition Alkylating Antineoplastics
Find the definition of the medical term Alkylating Antineoplastics. Alkylating Antineoplastics defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Alkylating Antineoplastics
| Alkylating Antineoplastics Medical Condition |
|---|
What's The Definition Of The Medical Condition Alkylating Antineoplastics?
A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA, Drug Evaluations Annual, 1994, p2026)
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Lupus Profundus ‐ A type of lupus erythematosus characterized by deep dermal or…
- Ethyl Alcohol ‐ A clear, colorless liquid rapidly absorbed from the gastrointestinal…
- Injury, Back ‐ General or unspecified injuries to the posterior part of the…
- Pharmacy Services ‐ Total pharmaceutical services provided by a qualified pharmacist.…
- Equipment Hazards ‐ Freedom of equipment from actual or…
- Syndrome, Conus Medullaris ‐ Acute and chronic conditions characterized by external mechanical…
- Indoleamine 2,3-Dioxygenase ‐ A protohemoprotein. Forms formylkynurenine from L-tryptophan…
- Molteno Implants ‐ Devices implanted to control intraocular pressure by allowing…
- Conditioned Reflex ‐ Learning that takes place when a conditioned stimulus is paired…
- Tac P55 Peptide ‐ Receptors present on activated T- and B-cells as a complex consisting…