About The Medical Condition Alkylating Antineoplastics
Find the definition of the medical term Alkylating Antineoplastics. Alkylating Antineoplastics defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Alkylating Antineoplastics
| Alkylating Antineoplastics Medical Condition |
|---|
What's The Definition Of The Medical Condition Alkylating Antineoplastics?
A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA, Drug Evaluations Annual, 1994, p2026)
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Limit Dextrinosis ‐ An autosomal recessive metabolic disorder due to deficient expression…
- Deductibles and Coinsurance ‐ Cost-sharing mechanisms that provide for payment by the insured…
- Sequence Analysis ‐ A multistage process that includes the determination of a sequence…
- Cell Death, Programmed ‐ One of the two mechanisms by which CELL DEATH occurs (the other…
- Hemispatial Neglect ‐ Cognitive disorders characterized by an impaired ability to perceive…
- Deficiency, IgA ‐ A dysgammaglobulinemia characterized by a deficiency of IMMUNOGLOBULIN…
- Platelet Adhesiveness ‐ The process whereby platelets adhere to something other than…
- Carcinomas, Anaplastic ‐ A malignant neoplasm made up of epithelial cells tending to infiltrate…
- Joint Prosthesis Implantations ‐ Partial or total replacement…
- Identity Disorder, Dissociative ‐ A dissociative disorder in which the individual adopts two or…