About The Medical Condition Allelic Loss
Find the definition of the medical term Allelic Loss. Allelic Loss defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Allelic Loss
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What's The Definition Of The Medical Condition Allelic Loss?
The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair. It is detected when heterozygous markers for a locus appear monomorphic because one of the alleles was deleted. When this occurs at a tumor suppressor gene locus where one of the alleles is already abnormal, it can result in neoplastic transformation.
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