About The Medical Condition Allelic Losses
Find the definition of the medical term Allelic Losses. Allelic Losses defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Allelic Losses
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What's The Definition Of The Medical Condition Allelic Losses?
The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair. It is detected when heterozygous markers for a locus appear monomorphic because one of the alleles was deleted. When this occurs at a tumor suppressor gene locus where one of the alleles is already abnormal, it can result in neoplastic transformation.
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