About The Medical Condition Alpha-D-Glucopyranosyl Isomer Etoposide
Find the definition of the medical term Alpha-D-Glucopyranosyl Isomer Etoposide. Alpha-D-Glucopyranosyl Isomer Etoposide defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Alpha-D-Glucopyranosyl Isomer Etoposide
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What's The Definition Of The Medical Condition Alpha-D-Glucopyranosyl Isomer Etoposide?
A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
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