About The Medical Condition Anaphylatoxins
Find the definition of the medical term Anaphylatoxins. Anaphylatoxins defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Anaphylatoxins
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What's The Definition Of The Medical Condition Anaphylatoxins?
The family of peptides C3a, C4a, C5a, and C5a des-arginine produced in the serum during complement activation. They produce smooth muscle contraction, mast cell histamine release, affect platelet aggregation, and act as mediators of the local inflammatory process. The order of anaphylatoxin activity from strongest to weakest is C5a, C3a, C4a, and C5a des-arginine. The latter is the so-called "classical" anaphylatoxin but shows no spasmogenic activity though it contains some chemotactic ability.
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