About The Medical Condition Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration
Find the definition of the medical term Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration. Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration
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What's The Definition Of The Medical Condition Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration?
Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
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