About The Medical Condition Antigen, CD3
Find the definition of the medical term Antigen, CD3. Antigen, CD3 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Antigen, CD3
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What's The Definition Of The Medical Condition Antigen, CD3?
Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA).
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