About The Medical Condition Antigens, HLA-C
Find the definition of the medical term Antigens, HLA-C. Antigens, HLA-C defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Antigens, HLA-C
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What's The Definition Of The Medical Condition Antigens, HLA-C?
Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the C locus on chromosome 6. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma).
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