About The Medical Condition Antiinflammatory Agents, Non Steroidal

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Antiinflammatory Agents, Non Steroidal

Antiinflammatory Agents, Non Steroidal Medical Condition Defined & Explained
Antiinflammatory Agents, Non Steroidal Medical Condition

What's The Definition Of The Medical Condition Antiinflammatory Agents, Non Steroidal?

Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or phospholipase C or may modulate T-cell function. (AMA Drug Evaluations Annual, 1994, p 1814-5)

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