About The Medical Condition Aryl Hydrocarbon Receptor

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Find the definition of the medical term Aryl Hydrocarbon Receptor. Aryl Hydrocarbon Receptor defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Aryl Hydrocarbon Receptor

Aryl Hydrocarbon Receptor Medical Condition Defined & Explained
Aryl Hydrocarbon Receptor Medical Condition

What's The Definition Of The Medical Condition Aryl Hydrocarbon Receptor?

Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.

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