About The Medical Condition ATP-Binding Cassette, Sub-Family B Proteins
Find the definition of the medical term ATP-Binding Cassette, Sub-Family B Proteins. ATP-Binding Cassette, Sub-Family B Proteins defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
ATP-Binding Cassette, Sub-Family B Proteins
| ATP-Binding Cassette, Sub-Family B Proteins Medical Condition |
|---|
What's The Definition Of The Medical Condition ATP-Binding Cassette, Sub-Family B Proteins?
A subfamily of transmembrane proteins from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS that are closely related in sequence to P-GLYCOPROTEIN. When overexpressed, they function as ATP-dependent efflux pumps able to extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Computer-Assisted Drug Therapy ‐ Adjunctive computer programs in providing drug treatment to…
- Tc-99m-Diethyl IDA ‐ A nontoxic radiopharmaceutical that is used in the clinical evaluation…
- Oncogene Protein src ‐ A tyrosine-specific protein kinase encoded by the v-src oncogene…
- Drugs, Investigational New ‐ Drugs which have received FDA approval for human testing but…
- Bepridil Monohydrochloride ‐ A long-acting calcium-blocking agent with significant anti-anginal…
- Insufficiencies, Kidney ‐ The inability of a kidney to excrete metabolites at normal plasma…
- Polyester, Pentosane Sulfuric ‐ A sulfated pentosyl polysaccharide with heparin-like…
- Chondroitinsulfatases ‐ A group of enzymes that catalyze the hydrolysis of various sulfate…
- Assassin Bug ‐ A family of winged insects of the suborder HETEROPTERA, called…
- Mesozoas ‐ Animals that have no…