About The Medical Condition ATP-Binding Cassette, Sub-Family C Proteins
Find the definition of the medical term ATP-Binding Cassette, Sub-Family C Proteins. ATP-Binding Cassette, Sub-Family C Proteins defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
ATP-Binding Cassette, Sub-Family C Proteins
| ATP-Binding Cassette, Sub-Family C Proteins Medical Condition |
|---|
What's The Definition Of The Medical Condition ATP-Binding Cassette, Sub-Family C Proteins?
A sequence-related subfamily of ATP-BINDING CASSETTE TRANSPORTERS that actively transport organic substrates. Although considered organic anion transporters, a subset of proteins in this family have also been shown to convey drug resistance to neutral organic drugs. Their cellular function may have clinical significance for CHEMOTHERAPY in that they transport a variety of ANTINEOPLASTIC AGENTS. Overexpression of proteins in this class by NEOPLASMS is considered a possible mechanism in the development of multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although similar in function to P-GLYCOPROTEINS, the proteins in this class share little sequence homology to the p-glycoprotein family of proteins.
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Nerve, Ophthalmic ‐ A sensory branch of the trigeminal (5th cranial) nerve. The ophthalmic…
- Malformation, Arnold-Chiari ‐ A group of congenital malformations involving the brainstem,…
- Alpha-Immunoglobulin ‐ Heavy chains found in the Fab and Fc fragments of IMMUNOGLOBULIN…
- Thyroiditides, Autoimmune ‐ Progressive enlargement of the thyroid gland, often associated…
- Artificial Heart ‐ A pumping mechanism that duplicates the output, rate, and blood…
- Progressive Paraparesis, Chronic ‐ Mild to moderate loss of bilateral lower extremity motor function,…
- Cells, Oxyntic ‐ Cells of the gastric glands which secrete hydrochloric acid and…
- Practice Patterns, Clinical ‐ Patterns of practice related to diagnosis and treatment as especially…
- Staff Workloads ‐ The total amount of work to be performed by an individual, a…
- Renographies, Radioisotope ‐ Graphic tracing over a time period of radioactivity measured…