About The Medical Condition Autosomal Dominant Hereditary Spastic Paraplegia

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Find the definition of the medical term Autosomal Dominant Hereditary Spastic Paraplegia. Autosomal Dominant Hereditary Spastic Paraplegia defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Autosomal Dominant Hereditary Spastic Paraplegia

Autosomal Dominant Hereditary Spastic Paraplegia Medical Condition Defined & Explained
Autosomal Dominant Hereditary Spastic Paraplegia Medical Condition

What's The Definition Of The Medical Condition Autosomal Dominant Hereditary Spastic Paraplegia?

A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progessive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8)

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