About The Medical Condition Basic Fibroblast Growth Factor
Find the definition of the medical term Basic Fibroblast Growth Factor. Basic Fibroblast Growth Factor defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Basic Fibroblast Growth Factor
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What's The Definition Of The Medical Condition Basic Fibroblast Growth Factor?
A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of ANGIOGENESIS. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).
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