About The Medical Condition Beta-Amyloid Protein Precursor
Find the definition of the medical term Beta-Amyloid Protein Precursor. Beta-Amyloid Protein Precursor defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Beta-Amyloid Protein Precursor
Beta-Amyloid Protein Precursor Medical Condition |
---|
What's The Definition Of The Medical Condition Beta-Amyloid Protein Precursor?
A precursor to the AMYLOID-BETA PROTEIN (beta/A4). Alterations in the expression of the amyloid beta-protein precursor (ABPP) gene, located on chromosome 21, plays a role in the development of the neuropathology common to both ALZHEIMER DISEASE and DOWN SYNDROME. ABPP is associated with the extensive extracellular matrix secreted by neuronal cells. Upon cleavage, this precursor produces three proteins of varying amino acid lengths: 695, 751, and 770. The beta/A4 (695 amino acids) or beta-amyloid protein is the principal component of the extracellular amyloid in senile plaques found in ALZHEIMER DISEASE; DOWN SYNDROME and, to a limited extent, in normal aging.
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Transphosphatase, ATP Choline ‐ An enzyme that is active in the first step of choline phosphoglyceride…
- Acid, Carbolic ‐ An antiseptic and disinfectant. It is active against a wide range…
- Ambystomas ‐ A genus of the Ambystomatidae family. The best known species…
- Faculties, Dental ‐ The teaching staff and members of the administrative staff having…
- Visual Hallucinations ‐ Subjectively experienced sensations in the absence of an appropriate…
- Facial Spasm, Unilateral ‐ Recurrent clonic contraction of facial muscles, restricted to…
- Superficial Peroneal Neuropathy ‐ Disease involving the common PERONEAL NERVE or its branches,…
- Incentive Plans, Employee ‐ Programs designed by management to motivate employees to work…
- Neurogenic Syncope ‐ Loss of consciousness due to a reduction in blood pressure that…
- Acute Myelocytic Leukemia ‐ Progressive, malignant disease of the myeloid tissue in which…