Beta Gene, erbA Medical Condition Defined & Explained

About The Medical Condition Beta Gene, erbA

Find the definition of the medical term Beta Gene, erbA. Beta Gene, erbA defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Beta Gene, erbA

Beta Gene, erbA Medical Condition
What's The Definition Of The Medical Condition Beta Gene, erbA? Retrovirus-associated DNA sequences (ERYTHROBLASTOSIS VIRUS, AVIAN, hence erbA) originally isolated from the avian erythroblastosis virus. The c-erbA proto-oncogene encodes the thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA proto-oncogenes have been identified, erbA-alpha and erbA-beta, each giving rise to at least two proteins. erbA-alpha is located at 17q21 on the long arm of chromosome 17. erbA-beta is located at 3p24 on the short arm of chromosome 3. The v-erbA oncogene potentiates cell transformation through inhibition of spontaneous differentiation of cells already transformed by the v-erbB gene and eliminates growth requirements of transformed erythroblasts.

Beta Gene, erbA Medical Condition

What's The Definition Of The Medical Condition Beta Gene, erbA?

Retrovirus-associated DNA sequences (ERYTHROBLASTOSIS VIRUS, AVIAN, hence erbA) originally isolated from the avian erythroblastosis virus. The c-erbA proto-oncogene encodes the thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA proto-oncogenes have been identified, erbA-alpha and erbA-beta, each giving rise to at least two proteins. erbA-alpha is located at 17q21 on the long arm of chromosome 17. erbA-beta is located at 3p24 on the short arm of chromosome 3. The v-erbA oncogene potentiates cell transformation through inhibition of spontaneous differentiation of cells already transformed by the v-erbB gene and eliminates growth requirements of transformed erythroblasts.

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