About The Medical Condition Beta-Protein Precursor, Amyloid
Find the definition of the medical term Beta-Protein Precursor, Amyloid. Beta-Protein Precursor, Amyloid defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Beta-Protein Precursor, Amyloid
| Beta-Protein Precursor, Amyloid Medical Condition |
|---|
What's The Definition Of The Medical Condition Beta-Protein Precursor, Amyloid?
A precursor to the AMYLOID-BETA PROTEIN (beta/A4). Alterations in the expression of the amyloid beta-protein precursor (ABPP) gene, located on chromosome 21, plays a role in the development of the neuropathology common to both ALZHEIMER DISEASE and DOWN SYNDROME. ABPP is associated with the extensive extracellular matrix secreted by neuronal cells. Upon cleavage, this precursor produces three proteins of varying amino acid lengths: 695, 751, and 770. The beta/A4 (695 amino acids) or beta-amyloid protein is the principal component of the extracellular amyloid in senile plaques found in ALZHEIMER DISEASE; DOWN SYNDROME and, to a limited extent, in normal aging.
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- BSIPSS ‐ Sampling of blood levels of the adrenocorticotropic hormone (ACTH)…
- Tosylarginine Methyl Ester ‐ Arginine derivative which is a substrate for many proteolytic…
- Disseminatum, Xanthoma ‐ Group of disorders which feature accumulations of active histiocytes…
- Normal Range ‐ The range or frequency distribution of a measurement in a population…
- Testing, Materials ‐ The testing of materials and devices, especially those used for…
- Lepidium meyenii ‐ A plant genus of the family CRUCIFERAE growing in Peru mountains.…
- Toxic Shock Syndrome ‐ Shock due to circulatory insufficiency caused most commonly by…
- Technic, Decision Support ‐ Mathematical or statistical procedures used as aids in making…
- Orobronze ‐ A trans-carotenoid pigment widely distributed in nature. The…
- Orf virus ‐ The type species of PARAPOXVIRUS which causes a skin infection…