About The Medical Condition Bone-Derived Transforming Growth Factor
Find the definition of the medical term Bone-Derived Transforming Growth Factor. Bone-Derived Transforming Growth Factor defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Bone-Derived Transforming Growth Factor
| Bone-Derived Transforming Growth Factor Medical Condition |
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What's The Definition Of The Medical Condition Bone-Derived Transforming Growth Factor?
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
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