About The Medical Condition BRCA2 Gene

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Find the definition of the medical term BRCA2 Gene. BRCA2 Gene defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

BRCA2 Gene

BRCA2 Gene Medical Condition Defined & Explained
BRCA2 Gene Medical Condition

What's The Definition Of The Medical Condition BRCA2 Gene?

A tumor suppressor gene (GENES, SUPPRESSOR, TUMOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast and ovarian cancer. It encodes a large, nuclear protein that is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev 2000;14(11):1400-6)

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