About The Medical Condition Buthionine Sulfoximine
Find the definition of the medical term Buthionine Sulfoximine. Buthionine Sulfoximine defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Buthionine Sulfoximine
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What's The Definition Of The Medical Condition Buthionine Sulfoximine?
A synthetic amino acid that depletes glutathione by irreversibly inhibiting gamma-glutamylcysteine synthetase. Inhibition of this enzyme is a critical step in glutathione biosynthesis. It has been shown to inhibit the proliferative response in human T-lymphocytes and inhibit macrophage activation. (J Biol Chem 1995;270(33):1945-7)
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