About The Medical Condition Caffeine Demethylase
Find the definition of the medical term Caffeine Demethylase. Caffeine Demethylase defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Caffeine Demethylase
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What's The Definition Of The Medical Condition Caffeine Demethylase?
A polycyclic aromatic hydrocarbon-inducible cytochrome which is of significant clinical interest due to the large number of drug interactions associated with induction and inhibition of theophylline. Caffeine is considered to be a model substrate for this enzyme. It also metabolizes theophylline and antipyrene. Environmental factors including cigarette smoking, charbroiled meat, cruciferous vegetables, and a number of drugs including phenytoin, phenobarbital, and omeprazole produce increases in CYP1A2 activity. (Ann Pharmacother 1995;29:619-24) EC 1.-.
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