About The Medical Condition Calcineurin
Find the definition of the medical term Calcineurin. Calcineurin defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Calcineurin
Calcineurin Medical Condition |
---|
What's The Definition Of The Medical Condition Calcineurin?
A calcium- and calmodulin-binding protein present in highest concentrations in the central nervous system. Calcineurin is composed of two subunits. A catalytic subunit, calcineurin A, and a regulatory subunit, calcineurin B, with molecular weights of about 60 kD and 19 kD, respectively. Calcineurin has been shown to dephosphorylate a number of phosphoproteins including histones, myosin light chain, and the regulatory subunit of cAMP-dependent protein kinase. It is involved in the regulation of signal transduction and is the target of an important class of immunophilin-immunosuppressive drug complexes in T-lymphocytes that act by inhibiting T-cell activation. EC 3.1.3.-.
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Nursing Administration Researchs ‐ Research concerned with establishing costs of nursing care, examining…
- Ion-Exchange Chromatography ‐ Separation technique in which the stationary phase consists of…
- Disease, Slow Virus ‐ Diseases of viral origin, characterized by incubation periods…
- Tenox BHA ‐ Mixture of 2- and 3-tert-butyl-4-methoxyphenols that is used…
- PrP (CJD) ‐ Abnormal isoform of prion proteins (PRIONS) resulting from a…
- Periodontal Pockets ‐ An abnormal extension of a gingival sulcus accompanied by the…
- Puncture Headache, Postdural ‐ Pain in the cranial region that may occur as an isolated and…
- Sexual Partner ‐ Married or single individuals who share sexual…
- Drusen, Optic Nerve ‐ Optic disk bodies composed primarily of acid mucopolysaccharides…
- Pipecuronium Dibromide, (3 beta)-Isomer ‐ A non-depolarizing neuromuscular blocking agent used during halothane…