About The Medical Condition CD117 Antigen
Find the definition of the medical term CD117 Antigen. CD117 Antigen defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
CD117 Antigen
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What's The Definition Of The Medical Condition CD117 Antigen?
A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEIN C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis. EC 2.7.11.-.
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