About The Medical Condition CD4 Antigen
Find the definition of the medical term CD4 Antigen. CD4 Antigen defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
CD4 Antigen
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What's The Definition Of The Medical Condition CD4 Antigen?
55-kD Glycoproteins originally defined as differentiation antigens on T-lymphocytes, but also found on other cells including monocytes/macrophages. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MHC (Major Histocompatibility Complex) Class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as HIV receptors, binding directly to the envelope protein gp120 on HIV.
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