About The Medical Condition CD4 Antigen

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Find the definition of the medical term CD4 Antigen. CD4 Antigen defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

CD4 Antigen

CD4 Antigen Medical Condition Defined & Explained
CD4 Antigen Medical Condition

What's The Definition Of The Medical Condition CD4 Antigen?

55-kD Glycoproteins originally defined as differentiation antigens on T-lymphocytes, but also found on other cells including monocytes/macrophages. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MHC (Major Histocompatibility Complex) Class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as HIV receptors, binding directly to the envelope protein gp120 on HIV.

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