About The Medical Condition Cerebellar Degeneration, Paraneoplastic
Find the definition of the medical term Cerebellar Degeneration, Paraneoplastic. Cerebellar Degeneration, Paraneoplastic defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Cerebellar Degeneration, Paraneoplastic
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What's The Definition Of The Medical Condition Cerebellar Degeneration, Paraneoplastic?
Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
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