About The Medical Condition Childhood Type Dermatomyositides
Find the definition of the medical term Childhood Type Dermatomyositides. Childhood Type Dermatomyositides defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Childhood Type Dermatomyositides
Childhood Type Dermatomyositides Medical Condition |
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What's The Definition Of The Medical Condition Childhood Type Dermatomyositides?
A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6)
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