About The Medical Condition Ciliary Neurotrophic Factor Receptor alpha Subunit
Find the definition of the medical term Ciliary Neurotrophic Factor Receptor alpha Subunit. Ciliary Neurotrophic Factor Receptor alpha Subunit defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Ciliary Neurotrophic Factor Receptor alpha Subunit
Ciliary Neurotrophic Factor Receptor alpha Subunit Medical Condition |
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What's The Definition Of The Medical Condition Ciliary Neurotrophic Factor Receptor alpha Subunit?
The ciliary neurotrophic factor receptor is comprised of three components: the ciliary neutrophilic factor receptor alpha subunit, the leukemia inhibitory factor receptor and the gp130 signal transducer. The specificity of the receptor for ciliary neurotrophic factor is determined by the alpha subunit, while signal transduction is mediated through the GP130 subunit. Although the receptor regulates neuronal development, it is structurally similar to the cytokine receptor for INTERLEUKIN-6; (RECEPTORS, INTERLEUKIN-6).
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