About The Medical Condition Class I Human Antigens

ClusterMed
  1. ClusterMed.info
  2. Medical Conditions
  3. C Illnesses And Diseases
  4. Cl
  5. Class I Human Antigens

Find the definition of the medical term Class I Human Antigens. Class I Human Antigens defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Class I Human Antigens

Class I Human Antigens Medical Condition Defined & Explained
Class I Human Antigens Medical Condition

What's The Definition Of The Medical Condition Class I Human Antigens?

Large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin. In humans, three structural genes on chromosome 6 code for the HLA-A; HLA-B and HLA-C antigens. In mice, three genes named K, D, and L on chromosome 17 code for the H-2 antigens. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during graft rejection and restrict cell-mediated lysis of virus-infected cells. They are primarily associated with rheumatologic diseases and certain malignant disorders.

More Medical Conditions

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z

Medical Conditions Definitions Of The Day