About The Medical Condition Classic Globoid Cell Leukodystrophy
Find the definition of the medical term Classic Globoid Cell Leukodystrophy. Classic Globoid Cell Leukodystrophy defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Classic Globoid Cell Leukodystrophy
| Classic Globoid Cell Leukodystrophy Medical Condition |
|---|
What's The Definition Of The Medical Condition Classic Globoid Cell Leukodystrophy?
An autosomal recessive inherited sphingolipidosis caused by a deficiency of GALACTOSYLCERAMIDASE leading to an accumulation of PSYCHOSINE in LYSOSOMES of the BRAIN; PERIPHERAL NERVES; LIVER; KIDNEY; and LEUKOCYTES. In the nervous sytem there is prominent central and peripheral demyelination. The infantile form presents at age 4-6 months with psychomotor retardation, MUSCLE SPASTICITY, and tonic spasms induced by minor stimuli. Death occurs within two years. Later onset forms of this disease are characterized by a less fulminant course. (From Menkes, Textbook of Child Neurology, 5th ed, pp195-7)
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Society, Pharmaceutical ‐ Societies whose membership is limited to…
- Monocyclic beta-Lactams ‐ Monocyclic, bacterially produced or semisynthetic beta-lactam…
- Ethanol-Induced Nervous System Disorders ‐ Acute and chronic neurologic disorders associated with the various…
- Herpetic Keratitis ‐ A superficial, epithelial Herpesvirus hominis infection of the…
- Arab Republic of Egypt ‐ A republic in northwest Africa. Its capital is Cairo. It was…
- Medullomyoblastoma ‐ A malignant neoplasm that may be classified either as a glioma…
- Ratios, International Normalized ‐ System established by the World Health Organization and the International…
- Iliohypogastric Nerve Neuralgia ‐ Intense or aching pain that occurs along the course or distribution…
- Fatigue Fracture ‐ Fractures due to the strain caused by repetitive exercise. They…
- Disadine ‐ An iodinated polyvinyl polymer used as topical antiseptic in…