About The Medical Condition Clozaril

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Find the definition of the medical term Clozaril. Clozaril defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Clozaril

Clozaril Medical Condition Defined & Explained
Clozaril Medical Condition

What's The Definition Of The Medical Condition Clozaril?

A tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent.

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