About The Medical Condition Collagenase, Clostridium histolyticum

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Find the definition of the medical term Collagenase, Clostridium histolyticum. Collagenase, Clostridium histolyticum defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Collagenase, Clostridium histolyticum

Collagenase, Clostridium histolyticum Medical Condition Defined & Explained
Collagenase, Clostridium histolyticum Medical Condition

What's The Definition Of The Medical Condition Collagenase, Clostridium histolyticum?

A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.

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