About The Medical Condition Collagenase Inhibitor
Find the definition of the medical term Collagenase Inhibitor. Collagenase Inhibitor defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Collagenase Inhibitor
Collagenase Inhibitor Medical Condition |
---|
What's The Definition Of The Medical Condition Collagenase Inhibitor?
A family of secreted proteins (TIMP-1; TIMP-2; and TIMP-3) that play a crucial role in regulating the activity of the secreted METALLOENDOPEPTIDASES (COLLAGENASES; stromelysins, GELATINASES). Of the three characterized, only TIMP-1 and TIMP-2 appear to have related primary structures and inhibitory properties. They influence the activation of the prometalloproteinase and act to modulate proteolysis of extracellular matrix, notably during tissue remodeling and inflammatory processes. On certain cell types, they can exhibit growth factor-like activity, and they can inhibit the tumorigenic and metastatic phenotype in cancer cells. (Pharmacol Ther 1993;59:329-41)
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Diverticulums, Esophagopharyngeal ‐ A diverticulum at the upper end of the esophagus through the…
- UDPGNAc ‐ Serves as the biological precursor of insect chitin, of muramic…
- Antibodies, Enhancing ‐ Antibodies that inhibit the reaction between antigen and other…
- BFU-E ‐ Committed, erythroid stem cells derived from myeloid stem cells.…
- Chemicals, Agricultural ‐ Chemicals used in agriculture. These include pesticides, fumigants,…
- Particle, Beta ‐ A stream of positive or negative electrons ejected with high…
- Resistance Gene, Multidrug ‐ Genes responsible for multidrug resistance resulting from their…
- Cytokeratin 8 ‐ A class of fibrous proteins or scleroproteins important both…
- Synthetase, S-Adenosylmethionine ‐ An enzyme that catalyzes the synthesis of S-adenosylmethionine…
- AHR-1911 ‐ Proposed topical anti-inflammatory agent that may release histamine…