About The Medical Condition Collagenase, Microbial
Find the definition of the medical term Collagenase, Microbial. Collagenase, Microbial defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Collagenase, Microbial
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What's The Definition Of The Medical Condition Collagenase, Microbial?
A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.
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