About The Medical Condition Complement 3a

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Find the definition of the medical term Complement 3a. Complement 3a defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Complement 3a

Complement 3a Medical Condition Defined & Explained
Complement 3a Medical Condition

What's The Definition Of The Medical Condition Complement 3a?

Smaller fragment formed when C3 convertase splits C3 into C3a and C3b. C3a is a 77-amino acid peptide that includes a carboxy-terminal arginine which is crucial for its biological activities. C3a causes symptoms of immediate hypersensitivity (anaphylaxis) including smooth muscle contraction, mast cell histamine release, and local inflammation. It is considered an anaphylatoxin along with C4a, C5a, and C5a des-arginine.

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