About The Medical Condition Complementarity-Determining Region
Find the definition of the medical term Complementarity-Determining Region. Complementarity-Determining Region defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Complementarity-Determining Region
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What's The Definition Of The Medical Condition Complementarity-Determining Region?
Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL).
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