About The Medical Condition Costimulatory Molecule, B7-1

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Find the definition of the medical term Costimulatory Molecule, B7-1. Costimulatory Molecule, B7-1 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Costimulatory Molecule, B7-1

Costimulatory Molecule, B7-1 Medical Condition Defined & Explained
Costimulatory Molecule, B7-1 Medical Condition

What's The Definition Of The Medical Condition Costimulatory Molecule, B7-1?

The natural ligand for the T-cell antigen CD28; (ANTIGENS, CD28); mediating T- and B-cell adhesion. CD80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes. The binding of CD80 to CD28 and CTLA-4 provides a co-stimulatory signal to T-cells and leads to greatly upregulated lymphokine production.

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