About The Medical Condition Cyclin-Dependent Kinase 1

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Find the definition of the medical term Cyclin-Dependent Kinase 1. Cyclin-Dependent Kinase 1 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Cyclin-Dependent Kinase 1

Cyclin-Dependent Kinase 1 Medical Condition Defined & Explained
Cyclin-Dependent Kinase 1 Medical Condition

What's The Definition Of The Medical Condition Cyclin-Dependent Kinase 1?

Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the cell cycle. It is the catalytic subunit of the MATURATION-PROMOTING FACTOR and complexes with both CYCLIN A and CYCLIN B in mammalian cells. The maximal activity of p34cdc2 is achieved when it is fully dephosphorylated. Protein p34cdc2, the product of the cdc2 gene in Schizosaccharomyces pombe, should not be confused with the unrelated product of the CDC2 gene in Saccharomyces cerevisiae that forms the large subunit of DNA polymerase III.

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