Cytotoxic T-Lymphocyte Medical Condition Defined & Explained

About The Medical Condition Cytotoxic T-Lymphocyte

Find the definition of the medical term Cytotoxic T-Lymphocyte. Cytotoxic T-Lymphocyte defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Cytotoxic T-Lymphocyte

Cytotoxic T-Lymphocyte Medical Condition
What's The Definition Of The Medical Condition Cytotoxic T-Lymphocyte? Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from natural killer cells (KILLER CELLS, NATURAL) and from KILLER CELLS mediating antibody-dependent cell cytotoxicity. There are two effector phenotypes: TC1 and TC2.

Cytotoxic T-Lymphocyte Medical Condition

What's The Definition Of The Medical Condition Cytotoxic T-Lymphocyte?

Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from natural killer cells (KILLER CELLS, NATURAL) and from KILLER CELLS mediating antibody-dependent cell cytotoxicity. There are two effector phenotypes: TC1 and TC2.

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