About The Medical Condition Degeneration, Striatonigral
Find the definition of the medical term Degeneration, Striatonigral. Degeneration, Striatonigral defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Degeneration, Striatonigral
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What's The Definition Of The Medical Condition Degeneration, Striatonigral?
A sporadic neurodegenerative disease with onset in middle-age characterized clinically by Parkinsonian features (e.g., MUSCLE RIGIDITY; HYPOKINESIA; stooped posture) and HYPOTENSION. This condition is considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Pathologic features include a prominent loss of neurons in the zona compacta of the SUBSTANTIA NIGRA and PUTAMEN. (From Adams et al., Principles of Neurology, 6th ed, p1075-6)
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