About The Medical Condition Desialylated Glycoproteins
Find the definition of the medical term Desialylated Glycoproteins. Desialylated Glycoproteins defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Desialylated Glycoproteins
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What's The Definition Of The Medical Condition Desialylated Glycoproteins?
Endogenous glycoproteins from which sialic acid has been removed by the action of sialidases. They bind tightly to their cell surface receptor which is located on hepatocyte plasma membranes. After internalization by adsorptive endocytosis they are delivered to lysosomes for degradation. Therefore receptor-mediated clearance of asialoglycoproteins is an important aspect of the turnover of plasma glycoproteins. They are elevated in serum of patients with hepatic cirrhosis or hepatitis.
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