About The Medical Condition Diamminodichloride, Platinum
Find the definition of the medical term Diamminodichloride, Platinum. Diamminodichloride, Platinum defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Diamminodichloride, Platinum
| Diamminodichloride, Platinum Medical Condition |
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What's The Definition Of The Medical Condition Diamminodichloride, Platinum?
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
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