About The Medical Condition Disease, Jakob-Creutzfeldt
Find the definition of the medical term Disease, Jakob-Creutzfeldt. Disease, Jakob-Creutzfeldt defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Disease, Jakob-Creutzfeldt
| Disease, Jakob-Creutzfeldt Medical Condition |
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What's The Definition Of The Medical Condition Disease, Jakob-Creutzfeldt?
A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
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