About The Medical Condition Dominant Hereditary Sensory Neuropathy, Type III

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Find the definition of the medical term Dominant Hereditary Sensory Neuropathy, Type III. Dominant Hereditary Sensory Neuropathy, Type III defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Dominant Hereditary Sensory Neuropathy, Type III

Dominant Hereditary Sensory Neuropathy, Type III Medical Condition Defined & Explained
Dominant Hereditary Sensory Neuropathy, Type III Medical Condition

What's The Definition Of The Medical Condition Dominant Hereditary Sensory Neuropathy, Type III?

An autosomal disorder of the peripheral and autonomic nervous systems limited to individuals of Ashkenazic Jewish descent. Clinical manifestations are present at birth and include diminished lacrimation, defective thermoregulation, orthostatic hypotension (HYPOTENSION, ORTHOSTATIC), fixed pupils, excessive SWEATING, loss of pain and temperature sensation, and absent reflexes. Pathologic features include reduced numbers of small diameter peripheral nerve fibers and autonomic ganglion neurons. (From Adams et al., Principles of Neurology, 6th ed, p1348; Nat Genet 1993;4(2):160-4)

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