About The Medical Condition Dystrophy, Duchenne Muscular
Find the definition of the medical term Dystrophy, Duchenne Muscular. Dystrophy, Duchenne Muscular defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Dystrophy, Duchenne Muscular
| Dystrophy, Duchenne Muscular Medical Condition |
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What's The Definition Of The Medical Condition Dystrophy, Duchenne Muscular?
An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
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